Each of the Abs inhibited viral plaque formation when added during the 1 h entry period (Fig 3D). However, while the Abs to nectin-1 also inhibited infection when cells were pretreated, and the Abs to gD inhibited infection if the virus were pretreated, the anti-PtdS and anti-Akt Abs were only inhibitory if added during viral entry. Here, AKT1 is linked to infection.