Small, but significant differences were observed in both type I and III IFN responses at 24 hours post viral infection between the control cells and the LD reduced cells; however, interestingly the cells stimulated with SeV compared to the viral mimic of dsRNA did not show the delayed IFN response, and in both cases the 24 hr IFN response was less than that at 8 hours post infection (Figs 5A and 6). Here, IFNA1 is linked to infection.