In the non-cancer human keratinocyte line HaCaT, TRPV4 currents were also found, but inward-rectification was less evident (see summary data in the bar chart in Fig 2), suggesting co-activation of other perhaps calcium-activated non-selective cation channels with a linear current-voltage relationship or Cl- channels, which, however, were not further characterized here. Here, TRPV4 is linked to cancer.