NPY and Alzheimer disease: In the 3xtg-AD group, 8 weeks of voluntary exercise resulted in significantly higher amounts of NPY neurons than 3xtg-AD group (3xtg AD: 98.9 ± 6.4 counts per section versus 3xtg AD+Ex: 147.2 ± 9.9 counts per section) (Fig 6A and 6B).