Interestingly, transcript levels of VEGFA varied among tumor samples and differential expression of VEGFA was not statistically significant in OSA tumors compared to osteoblast cells; however, this may have been due, in part, to variations in stroma/inflammatory cells within the tumor microenvironment or baseline necrosis within the primary tumor specimen that influenced the proportion of tumor cells. This evidence concerns the gene VEGFA and obstructive sleep apnea syndrome.