The heterozygous novel variant c.6061C>T, p.(Arg2021Cys) is located in the zona pellucida domain of TECTA, where several missense variants have been reported to be associated with dominant forms of HL [31], one of them altering the same amino acid (p.Arg2021His in Iwasaki et al. [19]). The gene discussed is TECTA; the disease is Hodgkins lymphoma.