Alterations in Fn splicing contribute to a variety of vascular diseases with an inflammatory component; stroke (Dhanesha et al., 2015), atherosclerosis (Tan et al., 2004), myocardial infarction (Arslan et al., 2011), organ transplant and other fibroses (Bhattacharyya et al., 2014; Booth et al., 2012). The gene discussed is FN1; the disease is Stroke.