The common biotherapies for the treatment of psoriasis include monoclonal antibody against interleukin IL-12 and IL-23 (ustekinumab) and anti-cytokine therapies (e.g., anti-tumor necrosis factor (TNF) therapies (adalimumab, etanercept, and infliximab)) [42]. The gene discussed is TNF; the disease is psoriasis.