22 Archer Archer HL HL Evans Evans J J Edwards Edwards S S Colley Colley J J Newbury-Ecob Newbury-Ecob R R O’Callaghan O’Callaghan F F Huyton Huyton M M O’Regan O’Regan M M Tolmie Tolmie J J Sampson Sampson J J Clarke Clarke A A Osborne Osborne J J CDKL5 mutations cause infantile spasms, early onset seizures, and severe mental retardation in female patients CDKL5 mutations cause infantile spasms, early onset seizures, and severe mental retardation in female patients J Med Genet J Med Genet 2006 2006 43 43 729 729 734 734 16611748 16611748. Here, CDKL5 is linked to infantile spasms.