Levels of BIM correlated most strongly with BCL-2, and also significantly correlated with BCL-XL, yet neither total MCL-1 nor high MW MCL-1 correlated with BIM, suggesting that this small sampling of primary AML samples was primarily dependent on BCL-2 followed by BCL-XL for survival (Supplementary Figure 6). This evidence concerns the gene BCL2 and acute myeloid leukemia.