Compared with controls (0.32±0.12 g/L), mild NAFLD (0.24±0.16 g/L, P < 0.05) and moderate NAFLD (0.25±0.17 g/L, P < 0.05) had significantly lower levels of Fetuin A, while serum fetuin A level tended to increase with the severity of NAFLD. The gene discussed is AHSG; the disease is metabolic dysfunction-associated steatotic liver disease.