TFRC and neoplasm: A trend towards association between primary tumor TfR1 H-score and sarcomatoid dedifferentiation was non-significant (p = 0.073, Figure 3E), however TfR1 staining intensity was significantly associated with sarcomatoid dedifferentiation (mean MSI= 1.9 for present vs. 1.2 for absent, p = 0.004) and the tumor percentage of sarcomatoid involvement (mean MSI = 1.2 for 0%; 1.3 for 1-50%, 2.3 for >50%; p = 0.013).