Additionally, multivariate logistic analysis revealed that advanced T stage (OR 3.0077, 95% CI 1.1436–8.9108; P = 0.0249) and high ezrin expression (OR 2.5128, 95% CI 1.0573–6.1922; P = 0.0369) were independent predictors of LN metastasis in CRC patients (Table 2). This evidence concerns the gene EZR and colorectal carcinoma.