First we examined endogenous levels of DRP1Ser616 in a panel of CRC cell lines carrying oncogenic KRAS mutations such as NCIH747, T84, VaCo5, SW620, LoVo, SW403, SKCO1, and SW480 including the wild-type controls HT55, CC20, and SW1222 (Figure 4A). The gene discussed is KRAS; the disease is colorectal carcinoma.