Comparing to normal control, the JAK/STAT pathway related genes (JAK1, JAK2, JAK3, STAT1, STAT2, STAT3 STAT5B, STAT6) were elevated in T-ALL patients (Supplementary Figure 1) The collected T-ALL patient samples were analysed by Western blotting to investigate JAK-STAT pathway activity and autophagy conditions. The gene discussed is JAK2; the disease is acute lymphoblastic leukemia.