TGFA and osteosarcoma: Previously, Wang et al demonstrated that miR-205 suppressed MG-63 cell proliferation and invasive capacity by targeting VEGFA [37]; Yang et al found that miR-205 functioned as an antioncogene by targeting TGF-α [38], while Zhang et al found that miR-205 inhibited osteosarcoma progression through targeting RUNX2 [39].