In an attempt to identify novel epigenetic regulators contributing to the silencing of TS miR-29b in MM, firstly we evaluated the potential correlation between miR-29b and the mRNA expression levels of histone methyltransferases with an oncogenic role in MM [23], such as EZH1, EZH2 and MMSET. The gene discussed is PRDM9; the disease is Miyoshi myopathy.