As shown in Figure 2B and 2C, the level of phosphorylated 4E-BP1 was significantly correlated with the IC50 of BEZ235, and the correlation between the level of phosphorylated 4E-BP1 and the percentage of growth inhibition of SCLC cells upon 1 μM RAD001 treatment was also significant. The gene discussed is EIF4EBP1; the disease is small cell lung carcinoma.