Recently Eng et al. identified in NCI60 breast cancer cell lines eleven novel single nucleotide polymorphisms on exonic or protein coding regions (in CFTR, ROBO1, BTBD12, DCT, SNTG1, SGCD, LPHN2, and GRIK1 genes) that are associated with sensitive or resistant phenotype to paclitaxel [13]. This evidence concerns the gene SLX4 and breast cancer.