Recently Eng et al. identified in NCI60 breast cancer cell lines eleven novel single nucleotide polymorphisms on exonic or protein coding regions (in CFTR, ROBO1, BTBD12, DCT, SNTG1, SGCD, LPHN2, and GRIK1 genes) that are associated with sensitive or resistant phenotype to paclitaxel [13]. The gene discussed is ROBO1; the disease is breast carcinoma.