In the univariate analysis, mortality was associated with bleeding (p = 0.005), Hb < 6g/dL (p-value = 0.021), cytolysis (p <10–3), hemophagocytic syndrome (p-value = 0.014) and treatment intolerance (p-value = 0.006) (Table 2). This evidence concerns the gene GSTM1 and hemophagocytic syndrome.