BDNF and schizophrenia: In another recent study by Marianthi Sotiropoulou et al [20], serum BDNF levels of 50 patients with schizophrenia who were treatment naïve were compared with a control group of 50 healthy people; the serum BDNF levels of the group with schizophrenia were detected to be statistically significantly lower than in the control group.