One of the more remarkable findings in this study was the presence of alpha-synuclein positive Lewy bodies, the pathological hallmark of PD, in several remaining neurons of the substantia nigra pars compacta of male rats exposed to 400 mg/kg BMAA on PND3, 4 and 5 and in female rats exposed to BMAA on PND3, 4, 5 and 6 (Figure 7C,D), and not in the brain tissue of control and vehicle control rats (Figure 7A,B). This evidence concerns the gene SNCA and Parkinson disease.