The list contained a number of already known proteins with altered abundance in PCa, obtained by comparative proteomics studies, such as Alpha-2-HS-glycoprotein (AHSG), Hemopexin (HPX), Protein S100-A9 (S100A9), Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4), Fibrinogen chains, Alpha-2-macroglobulin (A2M), Apolipoprotein A-IV (APOA4), Afamin (AFM), Kininogen-1 (KNG1), Protein AMBP (AMBP), Uromodulin (UMOD), members of the complement cascade, and zinc alpha 2 glycoprotein (AZGP1) (reviewed extensively in [10,11]). The gene discussed is A2M; the disease is posterior cortical atrophy.