In the present study, we confirmed the expression level of CXCL8 in PBMo-derived macrophages, TAM-like PBMo-derived macrophages and ESCC cell lines, and the expression of CXCR1 and CXCR2 on the ESCC cell lines. The gene discussed is CXCR1; the disease is esophageal squamous cell carcinoma.