Immunohistochemical analysis of HLA-G expression in tumor cells from 25 lymph node biopsies that were obtained at diagnosis showed that patients carrying a +3027 C/A genotype were all negative for HLA-G and only 5 cases having the wild type +3027 C/C genotype showed HLA-G expression (20%; Figure 6). The gene discussed is HLA-G; the disease is neoplasm.