Next, the stepwise multivariable logistic regression method was used to adjust a range of risk factors, including male gender, age, BMI, diabetes mellitus, hypertension, current smoker, MPV, levels of MMP-9, glucose, BNP, troponin I, GRACE score, impaired LV function (left ventricular ejection function <50%), Gensini score, WMI, and no-flow, which were associated with in-hospital mortality. The gene discussed is NPPB; the disease is Hypertension.