Squamous cell carcinoma antigen (SCC-Ag), carcinoembryonic antigen (CEA), cytokeratin 19 fragments (Cyfra21-1), carbohydrate antigen 19-9 (CA199) and carbohydrate antigen 72-4 (CA724) are commonly used in the management of esophageal cancer patients. This evidence concerns the gene CEACAM5 and esophageal cancer.