The profiles of gene expression, such as SNCA, Parkin, PINK1, LRRK2, UCHL1, TRIM24, MUL1, USP30, and DJ-1, have already been shown to be altered in the substantia nigra of PD patients, and may act as potential risk factors in PD diagnosis [2, 7–11]. This evidence concerns the gene USP30 and Parkinson disease.