CT26 tumor-bearing BLAB/c mice were i.t.-injected with PBS, 0.1 mg/kg LPS, 5 mg/kg PAH-CuS, and 5 mg/kg LPS-CuS and after 2 h, laser irradiation (1 W/cm2) was performed for 5 min. Here, DDX53 is linked to neoplasm.