Analysis of lung tissue microarrays for VDAC1 and AIF (10 healthy, 31 SCC and 21 AC) and for SMAC (20 healthy, 72 SCC and 72 AC) expression levels by IHC staining using specific antibodies revealed high expression of these proteins in lung cancer, as compared to healthy tissue (Figure 5A). The gene discussed is VDAC1; the disease is lung carcinoma.