Samples of cancer and healthy tissues from the same lung of NSCLC patients were analyzed by immunoblotting using specific antibodies to assess levels of the voltage-dependent anion channel 1 (VDAC1), hexokinase I (HK-I), SMAC/Diablo (SMAC), apoptosis inducing factor (AIF), mitochondrial anti-viral signaling (MAVS) and Bcl2. This evidence concerns the gene BCL2 and cancer.