Interestingly, only the mutated form of p53 showed a negative correlation with E6 in the cytoplasm (p=0.028, Spearman's rho: −0.140) (Stiasny et al. (July 2017) in print at Oncology Letters “The role of E6 oncoprotein, p53, p16, MDM2 and Galectin-3 for the clinical outcome of cervical cancer patients”). The gene discussed is LGALS3; the disease is cervical carcinoma.