A nuclear association between EzH2 and p-p65 was detected in colon tissues of AOM/DSS-treated MUC1.Tg mice by confocal microscopy (Figure 5A) and by co-immunoprecipitation in TNF-stimulated Caco-2 and HT-29 cells (Figure 5B). The gene discussed is EZH2; the disease is infectious otitis media.