We noticed that two relevant genes: DSC2 (encoding desmocollin 2, involved in cell adhesion, GO:0007155), and KRT17 (encoding keratin 17, involved in morphogenesis of an epithelium, GO:0002009; signal transduction GO:0007165; epidermis development, GO:0008544; positive regulation of cell growth, GO:0030307) are highly expressed in oral squamous cell carcinoma cell line, while they are down regulated in specimens from patients with lymph node involvement. Here, KRT17 is linked to oral cavity squamous cell carcinoma.