To investigate the role of lamin B2 in NSCLC growth, we transiently knocked down LMNB2 with LMNB2-RNAi or overexpressed LMNB2 with GFP-LMNB2 vector in A549 and H1299 lung cancer cell lines with their corresponding controls. Here, LMNB2 is linked to non-small cell lung carcinoma.