HOXA7 and KRT15 were repressed in the PCa Vcap, PC3, DU-145, LNcap and 22RV1 cells, and TGM4 was also down-regulated in PC3, DU145, LNcap and 22RV1 cells, which further confirmed the results of our microarray (Figure 3). Here, TGM4 is linked to posterior cortical atrophy.