CDH2 and neoplasm: The RCP gene is frequently amplified in cancer (Supplementary Figure S3A), and analysis of data from the TCGA collective Lung Squamous Cell Carcinoma panel (TCGA, provisional) revealed that the expression of N-cadherin protein is elevated in tumours in which the RCP gene is amplified (Supplementary Figure S3B), which is in agreement with our in vitro data.