STAT3 and central nervous system cancer: CD133+ C6 glioma cells were treated with STAT3 inhibitors WP1066 (5 μM) or S3 l-201 (50 μM) [36] for 24 h and p-STAT3, STAT3, CD133, Nestin, SSES-1, and NANOG were measured using Western blotting analysis.