An increase in SRSF1 expression was recently found to enhance relative levels of pro-oncogenic isoforms generated from the Mnk2 and RON genes which impair the p38-mitogen-activated protein kinase (MAPK) and mammalian target of rapamycin (mTOR) signaling pathways, consequently enhancing the migratory and invasive activities of different cancer cells [29,30]. Here, SRSF1 is linked to cancer.