As a predictor of the persistence/development of septic shock on the third day of observation (n = 28), the highest AUCs were found for PCT (0.766, 95% CI 0.665–0.867) and IL-6 (0.707, 95% CI 0.595–0.819) (Fig. 5, Supplementary Table 2). The gene discussed is IL6; the disease is septic shock.