EGFR and adenocarcinoma: Mutations in EGFR occur in approximately 15% of white and African American patients with NSCLC; 30% of NSCLC of Asian ethnicity; and are associated with adenocarcinoma histology, female gender, and nonsmoking status (Massarelli et al., 2013; Cote et al., 2011; Reinersman et al., 2011; Shigematsu et al., 2005; Tokumo et al., 2005).