EGFR and renal cell carcinoma: Additional studies are exploring the efficacy and safety of combining checkpoint inhibitors with chemotherapy, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, other mAbs (e.g., sunitinib [Sutent]/pazopanib [Votrient]), and radiation therapy in NSCLC and RCC (Amin et al., 2014; Antonia, Brahmer, Gettinger, Reardon, & Sampson, 2014a; Rizvi et al., 2014).