Firstly the PCOS should be diagnosed in early stages of infertility, secondly all PCOS patents above the age of 30 years should undergo DM screening with 75 g oral glucose, since fasting blood sugar might not be altered prior to establishment of DM, and thirdly lifestyle modification and insulin sensitisers should be prescribed for PCOS subjects (6). The gene discussed is INS; the disease is polycystic ovary syndrome.