For interaction results, the combination of older age with higher albumin level or longer treatment of years, and higher creatinine level with longer treatment years significantly decreased the log-odds of a low KPS score level, whereas for patients with the combination of primary kidney disease subclass (P_B) (Additional file 1: Table S1) and older age, and primary kidney disease subclass (P_B) and higher creatinine level, higher Hb levels and longer treatment years significantly increased the log-odds of having a low KPS score assessment. The gene discussed is ALB; the disease is kidney disorder.