In addition, the serum level of EMMPRIN in NSCLC patients with N0-N1 of lymph node metastasis was 91.78±9.97 pg/mL, which is lower than those lung cancer patients with N2-N3 of lymph node metastasis (107.66±14.39 pg/mL) (p < 0.001). This evidence concerns the gene BSG and non-small cell lung carcinoma.