Wen et al. [30] concluded that endostatin combined with radiotherapy can enhance the radiosensitivity of human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts, possibly by increasing endothelial cell and tumor cell apoptosis, attenuating tumor cell hypoxia, and modulating proangiogenic factor expression. Here, COL18A1 is linked to lung adenocarcinoma.