In the univariate analysis, age, gender, BMI, race, cause of liver disease, preoperative antiviral therapy, portal hypertension, tumor size, tumor number, type of PVTT, Child-Pugh class, initial modalities of treatment, number of TACE cycles, AFP level ≥ 400 ng/mL, and NLR (neutrophil-lymphocyte ratio) ≥4 were found to predict poor OS across the 7 articles. The gene discussed is AFP; the disease is liver disorder.