Next, Hdac6+/+ and Hdac6-/- BMDCs were infected for different times with Gram-negative bacteria (Salmonella Typhimurium and Escherichia coli DH5α) and Gram-positive bacteria (Listeria monocytogenes and Staphylococcus aureus) at a multiplicity of infection (MOI) of 10, with colony-formed units (CFUs) corresponding to intracellular live bacteria. This evidence concerns the gene HDAC6 and infection.