In a study of the murine AD model with given dietary phospholipid supplementation, phospholipids have been shown to enhance skin barrier and display the anti-inflammatory effect by regulating the covalently bound ω-hydroxy ceramides in the epidermis and decreasing the gene expression of both thymus activation-regulated chemokine (TARC) and thymic stromal lymphopoietin (TSLP) [42]. The gene discussed is CCL17; the disease is Alzheimer disease.