This miRNA has not been previously reported as associated with obesity, however among its targets are those involved in the pathogenesis of obesity-related complications, e.g., genes encoding interleukins (IL-6, IL-17B and IL-22), apolipoproteins (APOA5) and their receptors (APOBR). Here, APOA5 is linked to obesity due to melanocortin 4 receptor deficiency.