ACTA1 and malignant colon neoplasm: LTBP2 and CDH11 expression were both induced by TGF‐β and elevated in the stroma of colon cancer tissues.116 α‐SMA+ and vimentin+ cultured fibroblasts derived from 11 pairs of human gastric cancer and tumor‐adjacent tissues expressed different levels of proteins related to actin filaments, and this mirrored higher migration and proliferation rates of CAFs.117 Similarly, the cellular proteome of α‐SMA+ CAFs derived from two human invasive mammary ductal carcinoma and SMA− normal fibroblasts from matched non‐malignant adjacent region were different.